Investor Relations

Presentation Details:
Title: Local immunotherapy with INTASYL™ self-delivering RNAi targeting CTLA-4 provides robust tumor control in vivo
Abstract #: 537
Presenting Author: Ben Cuiffo
Date and Time: 9:00 am - 9:00 pm on Thursday, November 10th 
Location: Hall C 
Abstract 537 INTASYL Targeting CTLA-4 Provides Robust Tumor Control Invivo SITC 2022
 

Title: Intratumoral PH-109 INTASYL™ self-delivering RNAi targeting connective tissue growth factor (CTGF) provides efficacy in vivo in a mouse model of metastatic breast cancer
Abstract #: 1431
Presenting Author: Ben Cuiffo
Date and Time: 9:00 am - 9:00 pm on Thursday, November 10th 
Location: Hall C 
Abstract 1431 PH-109 Provides Efficacy in Metastatic Breast Cancer Model Invivo SITC 2022
 

Title: PH-804, an INTASYL™ self-delivering RNAi compound that targets TIGIT enhances NK cell cytotoxicity to tumor cells
Abstract #: 493
Presenting Author: Melissa Maxwell
Date and Time: 9:00 am - 9:00 pm on Thursday, November 10th 
Location: Hall C 
Abstract 493 PH-804 Enhances NK Cells Cytotoxicity to Tumor Cells SITC 2022
 

Title: Manufacturing of a clinical scale CD8 TIL product, AGX148, with and without gene silencing of PD-1 using self-delivering RNAi INTASYL^TM PH-762 (Presented by AgonOx, Inc.)
Abstract #: 409
Presenting Author: Colin Thalhofer (AgonOx, Inc.)
Date and Time: 9:00 am - 9:00 pm on Thursday, November 10th 
Location: Hall C 
 

Title: PH-894, an INTASYL™ self-delivering siRNA targeting BRD4, has dual functions to sensitize tumor cell killing and activate CD8 T cells
Abstract #: 1402
Presenting Author: Shenghua Zhou
Date and Time: 9:00 am - 8:30 pm on Friday, November 11th 
Location: Hall C 
Abstract 1402 PH-894 Has Dual Functions to Sensitize Tumor Cell Killing SITC 2022
 

Title: A Phase 1b study to evaluate the safety, tolerability, pharmacokinetics and anti-tumor activity of neoadjuvant use of PH-762 administered intratumorally in subjects with advanced melanoma (in collaboration with Gustave Roussy, Caroline Robert primary author)
Abstract #: 788
Presenting Author: Simon Fricker
Date and Time: 9:00 am - 8:30 pm on Friday, November 11th 
Location: Hall C 
Abstract 788 Phase 1b Study to Evaluate Use of PH-762 SITC 2022